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Cubs Host Diamondbacks in Weekend Series Opener

Both teams are looking to improve their playoff standings as they meet at Wrigley Field to kick off May baseball.

Category: Sports

The Chicago Cubs host the Arizona Diamondbacks at Wrigley Field for a weekend series opener on May 1, 2026, with first pitch set for 2:20 p.m. ET.

Why it matters: This matchup is important for both teams as they aim to solidify their positions in their respective divisions. The Cubs are looking to maintain momentum after a strong stretch, whereas the Diamondbacks hope to recover from recent struggles.

  • The Cubs are on a 12-3 run over the last two-plus weeks, winning 12 of their last 15 games.
  • Chicago's record stands at 19-12, placing them second in the NL Central.
  • The Diamondbacks, with a record of 16-14, are third in the NL West and have lost six of their last nine games.
  • Both teams are close to the top of their divisions, making this series potentially impactful for playoff positioning.

Driving the news: The Cubs are coming off a two-game winning streak against the San Diego Padres, including a tight 5-4 victory on April 29, 2026. Meanwhile, the Diamondbacks suffered a heavy 13-1 loss to the Milwaukee Brewers in their last outing.

  • In their recent series, the Cubs showcased strong offensive performance, highlighted by Matt Shaw's three hits and a home run.
  • The Diamondbacks' pitching staff has struggled, allowing 32 runs in their last three games.
  • Chicago is 11-5 at home this season, boasting the best home record in the National League.
  • This game marks the start of a three-game series between the two teams.

State of play: The starting pitchers for this matchup are Zac Gallen for the Diamondbacks and Colin Rea for the Cubs.

  • Zac Gallen holds a record of 1-1 with a 3.14 ERA across six starts this season.
  • Colin Rea, who is 3-1 with a 4.61 ERA, is making his fourth start and seventh appearance of the year.
  • Gallen has a career-low strikeout rate of 14.2% this season, raising concerns about his effectiveness.
  • Rea has shown promise but struggled in his last start, allowing six earned runs to the Los Angeles Dodgers.

The big picture: Both teams are vying for playoff spots early in the season, and this series could be a turning point.

  • The Cubs are currently ranked among the top four teams in MLB for runs scored, batting average, and OPS.
  • Arizona ranks 12th in wOBA and has a solid offensive lineup, but their recent form has been inconsistent.
  • Chicago's recent performance includes a plus-35 run differential, indicative of their offensive strength.
  • Both teams are expected to score heavily, with the over/under set at 7 runs for this game.

What they're saying: Analysts are predicting a competitive game based on recent trends and team performances.

  • "The Cubs have been one of the hottest teams in the league, and their lineup is deep," said a sports analyst.
  • "Gallen’s recent struggles could pose a challenge against a potent Cubs offense," another expert noted.
  • Betting odds favor the Cubs at -140 on the money line, indicating confidence in their ability to secure a victory.
  • "Expect a high-scoring affair, especially with both teams hitting the over frequently this season," added a betting analyst.

By the numbers: Key statistics shed light on what to expect from this matchup.

  • Cubs have won eight straight home games, their best stretch at Wrigley Field since 2017.
  • Chicago leads the league in on-base percentage at .353, compared to Arizona's .308.
  • The Cubs have allowed an average of just 7.6 hits per nine innings, ranking tied for fifth in MLB.
  • Arizona's bullpen has struggled, sitting with the fifth-worst ERA in the league.

Between the lines: The matchup offers intriguing player prop opportunities.

  • Ketel Marte has excelled against Rea, hitting .667 with two home runs in six at-bats.
  • Alex Bregman is also expected to shine, having a strong batting average at home this season.
  • Michael Busch could be due for a breakout game, as he has performed well historically against Gallen.
  • Both teams have a high rate of hitting the over this season, making the 7-run total enticing for bettors.

What's next: The series continues with two more games following this opener.

  • Fans can catch the game on Marquee Sports Network and DBACKS.TV.
  • The next game is also scheduled for Wrigley Field, with the Cubs hoping to extend their winning streak.
  • Injuries could impact both teams, with notable players on the injured list for each side.
  • The Cubs will look to maintain their dominance at home, where they have thrived this season.